site stats

Kif11 structure

Web18 jan. 2024 · KIF11 is a motor protein, which use energy to move and transport molecules within cells and have a diverse range of cellular functions. Important for the formation of … Web16 apr. 2024 · KIF11 inhibition induces bipolar mitotic spindle to collapse into a monopolar structure, and this histologic hallmark can be used as a surrogate marker for the anti …

Human Gene KIF11 (ENST00000676647.1) - genome.ucsc.edu

WebThis gene encodes a motor protein that belongs to the kinesin-like protein family. Members of this protein family are known to be involved in various kinds of spindle dynamics. The … WebDownload scientific diagram KIF11 localizes to the basal body of primary cilia in patient-derived glioblastoma tumorspheres. (a) Tumorspheres from GBM 08-387 were fixed and … the oceanview condos https://hkinsam.com

Increased Expression of KIF11/Kinesin5 Offsets Alzheimer Aβ …

WebThese proteins are classified into 14 subfamilies based on differences in their structure. The activity of kinesins supports several cellular functions such as meiosis, ... This family contains KIF11, a homotetrameric KIF … Webalso clearly illustrate the structural role of Kif11 in dendrites and in dendritic spines and are in agreement with previous studies showing that Kif11 regulates neuronal architecture … Web23 apr. 2024 · KIF11 knockdown exerted inhibitory effects on cell proliferation, migration, and invasion. ... with ZBP1, an mRNA-binding protein, to manipulate the mRNPs … the ocelot magazine

RCSB PDB - 3L9H: X-ray structure of mitotic kinesin-5 (KSP, KIF11…

Category:KIF11 - phosphosite.org

Tags:Kif11 structure

Kif11 structure

KIF11 Gene - Somatic Mutations in Cancer - Wellcome Sanger …

Web21 mrt. 2024 · KIF11 (Kinesin Family Member 11) is a Protein Coding gene. Diseases associated with KIF11 include Microcephaly With Or Without Chorioretinopathy, … WebKIF11, a plus end-directed kinesin, as a key gene in benzo(a)pyrene-induced non-small cell lung cancer. Five novel copy number variations detected in patients with …

Kif11 structure

Did you know?

WebKIF11 is a gene which is important for the development and maintenance of the brain, eyes, and lymphatic system. A disruption or the absence of this gene results in poor head … WebSWISS-MODEL Repository entry for P52732 (KIF11_HUMAN), Kinesin-like protein KIF11. Homo sapiens (Human) Toggle navigation SWISS-MODEL SWISS-MODEL. Modelling. …

Web11 sep. 2024 · Kif11 overexpression rescues cognition, long-term potentiation, and spine defects in mouse and cell models of Alzheimer’s disease Esteban M. Lucero, Ronald K. Freund, Noah R. Johnson, Breanna Dooling, Emily Sullivan, Olga Prikhodko, Md. Mahiuddin Ahmed, Mark L. Dell’Acqua, Heidi J. Chial, Huntington Potter Web5 mei 2024 · KIF11 is one of the 45 family members of kinesin superfamily proteins that functions as a motor protein in mitosis. Emerging evidence revealed that KIF11 plays …

Web25 okt. 2024 · Overexpression of KIF11, a gene associated with the structure and function of neurons, prevents and protects against cognitive decline in both mouse models and … Web11 apr. 2024 · Purpose The prognosis of advanced gastric cancer (GC) remains poor. It is urgent and necessary to find suitable prognostic markers. miR-619-5p is highly expressed in GC. However, the value of miR-619-5p and its target genes as prognostic biomarkers of GC is unclear. Methods RT-PCR was performed to verify the expression of miR-619-5p in …

Web11 jan. 2024 · This study aimed to investigate the mechanisms underlying the development of the androgen-independent phenotype in prostate cancer. Methylation patterns were detected in androgen-independent and androgen-dependent lymph node carcinoma of the prostate (LNCaP) prostate carcinoma cells based on methylated DNA …

WebIn order to identify the potential regions of KIF11 that recognize and interact with ZBP1, we dissected KIF11 protein structure, generated various truncated KIF11 cDNAs by PCR and subcloned the ... the ocelot from archerWeb4 mrt. 2024 · Finally, increased KIF11 expression in neuritic plaque-positive AD patients was found to correlate with better cognitive performance. Taken together, these mechanistic biochemical, cell biological, electrophysiological, animal model, and human data identify KIF11 as a key target of Aβ-mediated toxicity required to maintain synaptic structures … michigan\u0027s 11th congressional districtWeb28 mrt. 2024 · Hyaluronan is an extracellular matrix component that absorbs water in tissues and engages cell surface receptors, like Cluster of Differentiation 44 (CD44), to promote cellular growth and movement. Consequently, CD44 demarks stem cells in normal tissues and tumor-initiating cells isolated from neoplastic tissues. Hyaluronan mediated motility … michigan\u0027s 10th district mapWeb7 okt. 2009 · The structure of human kinesin-like motor protein Kif11/KSP/Eg5 in complex with ADP and enastrol. the ocheWebScore. KIF11. Kinesin-like protein KIF11; Motor protein required for establishing a bipolar spindle during mitosis. Required in non-mitotic cells for transport of secretory proteins … the ocelot pariahWebIn a male patient with microcephaly, bilateral chorioretinopathy, congenital bilateral lymphedema of the lower limbs, and mild learning difficulties (152950), originally reported … the ocenco groupWebKIF11 (also known as kinesin-5 and Eg5) is a homotetramer which cross-links anti-parallel microtubules in the mitotic spindle to maintain spindle bipolarity. [8] [9] … the oche the strand